Selenium toxicity may occur due to industrial exposures. Toxic symptoms include garlic breath odor, thick brittle fingernails, dry brittle hair, red swollen skin of the hands and feet, and nervous system abnormalities of numbness, convulsions, or paralysis. Selenium is produced as a byproduct of copper refining and is used in electronic semiconductors, as a decolorizing agent for ceramics and glass, and as a vulcanizing agent in the rubber industry. Normal levels of Selenium are important for the human diet. Selenium deficiency syndrome includes painful weak muscles and acute or chronic congestive heart failure due to cardiomyopathy that is sometimes fatal. Other findings noted in some cases of selenium deficiency include enlarged blood cells, depigmentation of skin and hair, and elevated transaminase and creatine kinase levels
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